Andrzej Pilc Selected Research

N,N'-dibenzhydrylethane-1,2-diamine dihydrochloride

7/2014	Activation of the mTOR signaling pathway in the antidepressant-like activity of the mGlu5 antagonist MTEP and the mGlu7 agonist AMN082 in the FST in rats.
4/2012	Opposing efficacy of group III mGlu receptor activators, LSP1-2111 and AMN082, in animal models of positive symptoms of schizophrenia.

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Andrzej Pilc Research Topics

Disease

12	Schizophrenia (Dementia Praecox) 12/2020 - 04/2012
7	Neurobehavioral Manifestations 01/2019 - 06/2013
6	Crohn Disease (Crohn's Disease) 01/2018 - 10/2013
5	Treatment-Resistant Depressive Disorder 06/2020 - 01/2013
5	Ulcerative Colitis 11/2016 - 01/2016
5	Mood Disorders (Mood Disorder) 01/2011 - 11/2003
4	Major Depressive Disorder (Major Depressive Disorders) 01/2020 - 03/2008
3	Psychotic Disorders (Schizoaffective Disorder) 08/2015 - 04/2012
3	Disease Progression 01/2015 - 11/2012
2	Central Nervous System Diseases (CNS Diseases) 10/2020 - 11/2007
2	Catalepsy 01/2019 - 09/2015
2	Depressive Disorder (Melancholia) 08/2018 - 11/2003
2	Prostatic Neoplasms (Prostate Cancer) 06/2017 - 11/2012
2	HIV Infections (HIV Infection) 01/2015 - 01/2013
2	Substance Withdrawal Syndrome (Withdrawal Symptoms) 11/2009 - 11/2004
1	Mental Disorders (Mental Disorder) 10/2020
1	Bipolar Disorder (Manic Depressive Psychosis) 06/2020
1	Brain Diseases (Brain Disorder) 10/2018
1	Hypertension (High Blood Pressure) 08/2018
1	Neoplasms (Cancer) 06/2017
1	Essential Hypertension 06/2017
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2017
1	Infections 10/2016
1	Pain (Aches) 08/2015
1	Social Phobia 04/2015
1	Anhedonia 01/2015
1	Essential Tremor (Essential Tremors) 08/2014
1	Tremor (Tremors) 08/2014
1	Decapitation 07/2014
1	Relapsing-Remitting Multiple Sclerosis 05/2014
1	Sudden Death 12/2013
1	Fistula 10/2013

Drug/Important Bio-Agent (IBA)

7	Antipsychotic Agents (Antipsychotics)IBA 12/2020 - 06/2013
6	Biological ProductsIBA 01/2018 - 01/2016
5	Antidepressive Agents (Antidepressants)IBA 10/2020 - 11/2003
5	ZincIBA 01/2015 - 11/2003
4	Ketamine FDA LinkGeneric 06/2020 - 01/2013
4	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 10/2018 - 11/2007
4	Adalimumab (Humira)FDA Link 11/2016 - 10/2013
4	LigandsIBA 01/2016 - 11/2007
3	Pharmaceutical PreparationsIBA 10/2020 - 05/2014
3	Haloperidol (Haldol)FDA LinkGeneric 01/2019 - 09/2002
3	Amphetamine (Amfetamine)FDA LinkGeneric 10/2018 - 04/2012
3	Proteins (Proteins, Gene)FDA Link 10/2018 - 01/2015
3	vedolizumabIBA 01/2018 - 01/2016
3	Infliximab (Remicade)FDA Link 10/2016 - 10/2013
3	Glutamic Acid (Glutamate)FDA Link 01/2016 - 11/2004
3	N1- (3,4- dichlorophenyl)- cyclohexane- 1,2- dicarboxamideIBA 01/2015 - 08/2013
3	Dizocilpine Maleate (Dizocilpine)IBA 12/2013 - 06/2013
2	N,N'- dicyclopentyl- 2- methylsulfanyl- 5- nitro- pyrimidine- 4,6- diamineIBA 01/2019 - 09/2015
2	MagnesiumIBA 08/2018 - 09/2008
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2018 - 10/2013
2	Biomarkers (Surrogate Marker)IBA 01/2018 - 01/2016
2	Neurotransmitter Agents (Neurotransmitter)IBA 01/2018 - 03/2008
2	Serotonin (5 Hydroxytryptamine)IBA 06/2017 - 08/2015
2	golimumab FDA Link 10/2016 - 01/2016
2	efavirenz (Sustiva)FDA Link 01/2015 - 01/2013
2	RNA (Ribonucleic Acid)IBA 01/2015 - 01/2013
2	Ritonavir (Norvir)FDA Link 01/2015 - 01/2013
2	N,N'-dibenzhydrylethane-1,2-diamine dihydrochlorideIBA 07/2014 - 04/2012
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 12/2013 - 01/2013
2	LSP1 2111IBA 06/2013 - 04/2012
2	Morphine (MS Contin)FDA LinkGeneric 11/2009 - 11/2004
1	cinnabarinic acidIBA 12/2020
1	KynurenineIBA 12/2020
1	EsketamineIBA 01/2020
1	Cholinergic Agents (Cholinergics)IBA 01/2019
1	1- (4- methoxybenzyl)- 5- (trifluoromethoxy)indoline- 2,3- dioneIBA 01/2019
1	3- amino- N- (4- methoxybenzyl)- 4,6- dimethylthieno(2,3- b)pyridine- 2- carboxamideIBA 01/2019
1	VU0357017IBA 01/2019
1	Muscarinic M4 ReceptorIBA 10/2018
1	Messenger RNA (mRNA)IBA 01/2018
1	gamma-Aminobutyric Acid (GABA)IBA 01/2018
1	Serotonin AgentsIBA 01/2018
1	Ustekinumab (CNTO 1275)FDA Link 01/2018
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 06/2017
1	norclozapineIBA 12/2016
1	clozapine N-oxideIBA 12/2016
1	Clozapine (Clozaril)FDA LinkGeneric 12/2016
1	Prednisolone (Predate)FDA LinkGeneric 05/2016
1	Azathioprine (Imuran)FDA LinkGeneric 05/2016
1	Mesalamine (Mesalazine)FDA LinkGeneric 05/2016
1	Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric 05/2016
1	LSP4-2022IBA 01/2016
1	GABA Receptors (GABA Receptor)IBA 01/2016
1	3- cyano- N- (1,3- diphenyl- 1H- pyrazol- 5- yl)benzamideIBA 09/2015
1	Pregabalin (Lyrica)FDA Link 04/2015
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2015
1	4-iodo-2,5-dimethoxyphenylisopropylamine (DOI-P)IBA 01/2015
1	N-Methylaspartate (NMDA)IBA 09/2014
1	metabotropic glutamate receptor 4IBA 08/2014
1	HarmalineIBA 08/2014
1	Synapsins (Synapsin I)IBA 07/2014
1	Dimethyl FumarateIBA 05/2014
1	AntibodiesIBA 10/2013

Therapy/Procedure

15	Therapeutics 08/2018 - 11/2003
1	Drug Tapering 10/2020
1	Intranasal Administration 10/2020
1	Investigational Therapies (Experimental Therapy) 01/2017
1	Biological Therapy 01/2016